eeg-spike-neuroscience-classification-benchmarks-multi-agent-llm-pipeline-planning CLM-0562
mechanismsingle paperReviewed by AI

On EEG and spike neuroscience classification benchmarks, a multi-agent LLM pipeline with planning, code generation and closed-loop retry does not by itself beat a single-shot LLM coding agent; the measured gain comes from making domain-specific pre-trained neural models addressable through one interface and choosing among them per dataset.

Capability: Competence in a specialist domain

Observed on

Three public datasets (Alzheimer's EEG, Parkinson's EEG, working-memory spikes), nine frozen pre-trained neuroscience models used as feature extractors, GPT-5.2 agents, 8 seeds per.

Sources

  • Validated by: Primary metric (macro F1 or balanced accuracy) over 8 trials against general agents, scientific agents and two single-shot LLM coding baselines; plus a 'Vanilla' arm (same architecture, pre-trained models removed), whose initial round scored below Codex on AD (49.80 vs 51.01) and PD (64.52 vs 65.52), and a held-out fixed-model comparison on WM (POYO-1 +6.82 pp over handcrafted features, better on 7 of 8 seeds).. [truncated]
Reviewed by AI (Claude Opus 5)Last checked: 2026-10-24Evidence activity: not checked yet
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Notes

Drafted from the paper by a model and filed unreviewed. Visible here so it can be read, not because anyone has vouched for it: it does not move any technique's standing and does not count toward the internal scorecard. Drafted confidence: medium. Falsifier as drafted: An orchestration-only arm (no domain pre-trained models in the tool registry) matching or beating single-shot LLM coding agents on the same benchmarks and seeds, or the per-dataset selection giving no gain over always using one fixed pre-trained model.