medical-llms-given-clinical-practice-guideline-context-asked-produce CLM-0609
observationsingle paperReviewed by AI

When medical LLMs are given a clinical practice guideline in context and asked to produce the decision pathway a case requires, final-outcome accuracy does not track adherence to the guideline-defined step sequence: models can reach the right outcome while omitting, reordering, skipping or padding steps, and medically fine-tuned models score no better on pathway consistency than the general models they were tuned from.

Capability: Competence in a specialist domain

Observed on

16 models on 7,458 cases built from 440 English and Chinese guidelines; guideline text supplied in context; pathway consistency measured by an LLM judge scoring step matches aggreg.

Sources

  • Validated by: Pairwise human preference study on 200 sampled pathway pairs: the metric agreed with aggregated human preference 90.0% of the time, equal to the 90.0% agreement between two annotators; results held across three aggregation methods and two judge models (Kendall's W 0.70-0.87).. Measured across 16 models in single-turn and multi-turn settings. Qwen3-235B-A22B had the highest single-turn accuracy (75.81%) but not the lowest pathway cost (GPT-5.4 at 28.41%); Baichuan-M3-235B, fine-tuned from Qwen3-235B-A22B, had worse pathway cost in both settings. [truncated]
Reviewed by AI (Claude Opus 5)Last checked: 2026-10-24Evidence activity: not checked yet
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Notes

Drafted from the paper by a model and filed unreviewed. Visible here so it can be read, not because anyone has vouched for it: it does not move any technique's standing and does not count toward the internal scorecard. Drafted confidence: medium. Falsifier as drafted: Showing that outcome accuracy and pathway consistency rank models the same way on this benchmark, or that medically fine-tuned models consistently beat their base models on pathway consistency.